Is this why artificial sweetners make you fat?

It is definitely worth reading the whole of this excellent post, but for now have a look at this extract:

One question is, why does fructose (and alcohol) intake result in visceral fat, and not the more benign sub-cutaneous or intra-muscular fat? I have one possible explanation that I like to term the ‘circulatory fat deposition model.’ When you ingest a toxin like fructose or alcohol, the body automatically increases circulation to the vital organs (and in particular the liver) so that it can be filtered out of the blood stream. Since any ingested substance will naturally diffuse to even concentration throughout the blood, this is the only way to preferentially increase the flux of toxin to the liver.

Fructose is well known to contribute greatly to post-meal triglyceride levels (Chong et al., 2007). The liver takes fructose and produces palmatic acid (i.e. a stable saturated fat) from it. It then releases that fat into the blood stream. Since the filtering of fructose isn’t instant, the circulation in the body core is still heightened. As a result, the visceral fat tissues see a higher rate of triglyceride flux than the more benign skin or muscle fat (Note: flux in a scientific sense typically means mass or volume per second — put those Star Trek thoughts out of your mind). The visceral fat, which sees the most fabricated triglycerides floating on by, also happens to absorb the most. Hence fructose tends to promote visceral fat. On the other hand, if you ingest excess calories in the form of fat, it’s not any more likely to deposit around the liver than it is you thighs, so it’s not nearly so dangerous.

One sees a similar effect with amateur body-builders who ingest calorie-heavy shakes and energy drinks after or during exercise where their muscles are generating a lot of lactic acid. The body increases blood flow to those muscles to remove the lactic acid, but the fat deposits inside the muscle also see a much higher flux of fat and fat-building substrate as a result. This results in a characteristic thick and pasty muscle texture without a lot of functional power. Think of well-marbled beef steak.

If this hypothesis is true then combining dietary fat with any chemical that requires extensive liver processing (e.g. caffeine, artificial sweeteners) would also tend to result in visceral fat deposition.


5 Responses to “Is this why artificial sweetners make you fat?”

  1. JetDoc Says:

    Can artificial sweetners make you fat?
    I've been drinking diet sodas for YEARS because I'm borderline diabetic, and trying to control my sugar intake… Now the big news stories on TV say that artificial sweetners and caffine in diet sodas both contribute to weight gain and poorly controlled insulin levels. What's next?

  2. Alex Says:

    Diet sodas contain lots of chemicals (Imulsifiers, sweeteners, flavourings) this makes up for the sugar loss. Your question is easy, If you drink lotss of diet soda you will become obese if you drink them in moderation its not that bad.
    References :

  3. we are in love with eachother Says:

    to much of anything will so be careful
    References :

  4. Fan_Of_MsInd84 Says:

    Yes, artificial sweeteners makes you fat, and too much caffeine gives you high blood pressure. Just like too much salt gives you high cholesterol. I am a truck driver and the DOT (Dept of Transportation) has many guidelines to getting a clean bill on a DOT medical card. DOT certified doctor's will tell you that artificial sweetener is bad for you, and too much caffeine is bad for you, so is salt. The best thing to drink regularly is water. The best thing to eat is a lot of salads. And no dressing. Maybe oil and vinegar, but very little. And not too much red meat, that makes you fat as well. (Even though most of us love that Sirloin Steak), Chicken is good for you, grilled not fried. And some truckers claim, the bread makes you fat too. So no bread. You can still have a soda/pop once in a while, but the best thing for you is water. It cleans out the system. Hope this answered your question.
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    D.O.T doctor's say it. PS: Did you know that Coca Cola has stuff in it that is flamable and corrosive? I pulled a load from the Coca Cola Manufacturing plant in Atlanta GA once, 3 years ago, had to placcard it flamable and corrosive. That day I started drinking water.

  5. second-sun Says:

    Not true. Why do you believe the news?

    Artificial sweeteners such as Aspartame canot be broken down and used as energy. So unless someone mixes in sugar with the artificial sweetener (like some restoraunts do) it doesnt work.

    It does give you cancer though, but over a long period of time and only if you use it constantly.
    References :

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